The Inhibitory Effect of Peganum Harmala Plant Extracts on Certain Pathogenic Bacteria

Abstract

It was shown in this study that extracts of the peganium harmala plant have an effect in inhibiting some pathogenic bacteria, including Klebsiella, Staphylococcus, and Eshericiacoli. The effect was variable against the target bacterial species, not only between the types of solvents used in the extraction, but even with the use of different concentrations of the same solvent. The results of the study of the inhibitory effectiveness of the extracts varied, according to the diversity of concentrations and parts from which they were extracted, as the sulfuric acid extract was the most efficient in causing inhibition of bacterial growth, as it recorded the highest rates of inhibition, reaching 42 mL. While the alcohol extract is highly effective compared to the aqueous extract in many results, sometimes no effect appears for some species at certain concentrations. The water was less effective compared to its counterparts, but it was effective at specific concentrations, and its highest effect rate was 30 mL. When testing the effect of some commonly used antibiotics against the bacterial species targeted in this research and comparing them to the results of testing the extracts used, it was found that the antibiotics had less effect than the effect of the Haramel plant extracts.